Endometrial dating histology
According to the histological dating and transcriptomic profile of endometrium of hormone replacement cycle in control group, to explore the effectiveness of intervention by advanced or delayed personal embryo transfer .
The establishment of standard control group: Frozen embryo transfer patients according to the inclusion and exclusion criteria were evaluated for histological dating and transcriptomic profile by endometrial biopsy on day P＋7 in an HRT cycle.
The appearance greatly resembles the inactive endometrium seen in postmenopausal women, as both prepubertal and postmenopausal endometria do not exhibit any proliferative or secretory changes that are hormone dependent.
The endometrium in the reproductive female may be considered to comprise of a deeper basal layer and a superficial functional layer.
The aim of this study is to explore the transcriptomic profile of endometrial receptivity in different histological dating of hormone replacement cycle and its clinical application.
The epithelium contains mitotic cells and increase in tortuosity in the mid and late proliferative phase.
The stromal edema is most marked at the mid-proliferative phase.
During the proliferative phase the endometrial glands, stroma and vascular endothelium all proliferate leading to an increased volume of the endometrium.
The glands are lined by a stratified columnar epithelium with interspersed ciliated cells.
The phases seen in a classic 28-day cycle are distributed as follows: Day 1-5 Menstrual Phase Day 5-14 Proliferative Phase Day 14-15 Ovulation Day 15-28 Secretory Phase The first day of bleeding is considered Day 1 of the cycle and heralds the onset of the menstrual phase.